It has been predicted that by the year 2020 there will be an increase by almost 75% in the global CVD burden. The Global Burden of Disease study reported the estimated mortality from CAD in India at 1.6 million in the year 2000. But the mortality remains high among Indians.
With introducing a huge armamentarium of invasive and non-invasive therapeutic strategies, the mortality related to ACS has significantly reduced in the developed world over the past 20 years. All conventional risk factors were represented in all types of ACS but hypertension and tobacco abuse were more consistent risk factors associated with STEMI.Ĭoronary artery disease (CAD) is the leading cause of mortality and morbidity in the world and acute coronary syndrome (ACS), which encompass ST-elevation myocardial infarction, non-ST-elevation myocardial infarction (NSTEMI), and unstable angina (UA) are the commonest causes of mortality in patients with CAD. There was a marked preponderance of STEMI in younger patients but it was less marked in older patients, according to the study. Thrombolysis was advocated in three (5.7%) patients with Streptokinase (SK) and two patients with Tenecteplase (TNK). Coronary artery bypass graft (CABG) was done in five (5/100) patients only. A majority of patients underwent percutaneous intervention (69% of 100). There was a highly significant association between a specific line of treatment and type of ACS (p < 0.0001). Single vessel disease (SVD) patients dominated both the STEMI and UA groups. There was significant variation between risk stratification of ACS patients by Thrombolysis in Myocardial Infarction and Global Registry of Acute Cardiac Events scores. Tobacco abuse was more common in STEMI patients as compared to other types of ACS. A majority of patients with ACS were seen in the 55–74 years age group. Results:Īge groups and type of ACS were having a statistically significant association (p = 0.04). Sociodemographic data, anthropometric data, clinical history, significant past medical history, medications, current clinical status of the patient, and investigations including electrocardiogram (ECG), electrocardiogram (ECHO), and coronary artery graft. The Research Ethics Committee of the Hospital reviewed and approved the study protocol. The study was carried out in the Cardiology Department of Batra hospital and Medical Research Center, New Delhi, India. The aim of the study was to define the demographic profile of patients with ACS in a tertiary care center, to identify risk factors in the profile of patients with ACS, to learn about the management of ACS in tertiary health care centers, and to estimate in-hospital outcomes in ACS patients at a tertiary health care center. Death and morbidity are caused by coronary artery disease (CAD) and acute coronary syndrome (ACS), which include ST-elevation myocardial infarction (STEMI) and unstable angina (UA), are the most common causes of death among those with CAD.
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